Evaluation of the ability of fatty acid metabolism signature to predict response to neoadjuvant chemoradiotherapy and prognosis of patients with locally advanced rectal cancer

Neoadjuvant chemoradiotherapy (nCRT) is widely used to treat patients with locally advanced rectal cancer (LARC), and treatment responses vary.Fatty acid metabolism (FAM) is closely associated with carcinogenesis and cancer progression.In this study, we investigated the vital role of FAM on the gut microbiome and metabolism in the context of cancer

read more


PERIOPERATIVE CHANGES OF MICROBIOCENOSIS IN SURGICAL TREATMENT OF PATIENTS WITH COLORECTAL CANCER (review of literature)

Perioperative changes in microbiocenosis in patients with oncological diseases is the widely researched theme in colorectal surgery.In particular, the role of the colon microbiome in the development of purulent-inflammatory postoperative complications and possible significance in cancer disease recurrence have been actively investigated.Data on the

read more

Correlates of Nonanemic Iron Deficiency in Restless Legs Syndrome

Objective: Iron deficiency anemia (IDA) is a well-known cause of secondary restless legs syndrome (RLS).Iron deficiency without anemia (IDNA) is insidious, and its association with RLS is less evaluated.We investigate prevalence and features of IDNA in a consecutive cohort of patients with RLS.Methods: We included sequential primary RLS patients an

read more